Hydrangea flower leaves are considered toxic because they contain cyanogenic glycoside compounds and release hydrogen cyanide compounds when ingested. However, the roots can be used in traditional medicine as antioxidants and to treat kidney disease.

Hydrangea flower root is known to treat multiple sclerosis (a disease that affects the central nervous system), psoriasis (very fast skin renewal), kidney stones, diabetes, and arthritis. Besides medicine, this plant can be used as aromatherapy.

Hydrangea flowers have different meanings based on different beliefs and stories throughout. According to Japanese legend, the hydrangea flower is meant to apologize to the Japanese emperor, who neglected the woman he loved because of state affairs, and to show how much he cares for her.

According to the plot, a bouquet of hydrangea flowers means an expression of gratitude and heartfelt feelings on the part of the donor for understanding the recipient of the flower. But there are stories in the Middle Ages: some believed that a young woman holding a hydrangea flower in her hands would never find a life partner.

Like ornamental plants in general, hydrangea flowers can be grown from seed. But now people are choosing to grow hydrangea flowers using simpler techniques such as stem cuttings and tissue culture.

Hydrangea flowers are grown from stem cuttings only using the center of the hydrangea stem that does not flower. This method requires hydrangea flower stalks as short as 12 cm. In addition, with tissue culture methods, hydrangea flowers can be produced faster, in large and uniform quantities.